Development of immunoglobulin variable heavy chain gene consensus probes with conjugated 3' minor groove binder groups for monitoring minimal residual disease in childhood acute lymphoblastic leukaemia.
Identifieur interne : 003223 ( Main/Exploration ); précédent : 003222; suivant : 003224Development of immunoglobulin variable heavy chain gene consensus probes with conjugated 3' minor groove binder groups for monitoring minimal residual disease in childhood acute lymphoblastic leukaemia.
Auteurs : M. Uchiyama [Japon] ; C. Maesawa ; A. Yashima ; T. Itabashi ; T. Satoh ; M. Tarusawa ; M. Endo ; Y. Takahashi ; S. Sasaki ; S. Tsuchiya ; Y. Ishida ; T. MasudaSource :
- Journal of clinical pathology [ 0021-9746 ] ; 2003.
Descripteurs français
- KwdFr :
- Alignement de séquences, Chaines lourdes des immunoglobulines (génétique), Enfant, Humains, Leucémie-lymphome lymphoblastique à précurseurs B et T (diagnostic), Maladie résiduelle, Réaction de polymérisation en chaîne (), Réarrangement des gènes des chaines lourdes des lymphocytes B, Région variable d'immunoglobuline (génétique), Sondes oligonucléotidiques, Séquence consensus (génétique).
- MESH :
- diagnostic : Leucémie-lymphome lymphoblastique à précurseurs B et T.
- génétique : Chaines lourdes des immunoglobulines, Région variable d'immunoglobuline, Séquence consensus.
- Alignement de séquences, Enfant, Humains, Maladie résiduelle, Réaction de polymérisation en chaîne, Réarrangement des gènes des chaines lourdes des lymphocytes B, Sondes oligonucléotidiques.
English descriptors
- KwdEn :
- Child, Consensus Sequence (genetics), Gene Rearrangement, B-Lymphocyte, Heavy Chain, Humans, Immunoglobulin Heavy Chains (genetics), Immunoglobulin Variable Region (genetics), Neoplasm, Residual, Oligonucleotide Probes, Polymerase Chain Reaction (methods), Precursor Cell Lymphoblastic Leukemia-Lymphoma (diagnosis), Sequence Alignment.
- MESH :
- chemical , genetics : Immunoglobulin Heavy Chains, Immunoglobulin Variable Region.
- diagnosis : Precursor Cell Lymphoblastic Leukemia-Lymphoma.
- genetics : Consensus Sequence.
- methods : Polymerase Chain Reaction.
- Child, Gene Rearrangement, B-Lymphocyte, Heavy Chain, Humans, Neoplasm, Residual, Oligonucleotide Probes, Sequence Alignment.
Abstract
To develop immunoglobulin heavy chain variable (VH) gene probes that are shorter and more flexible in position for monitoring minimal residual disease (MRD) in childhood leukaemia (ALL), using minor groove binder (MGB) technology.
DOI: 10.1136/jcp.56.12.952
PubMed: 14645357
Affiliations:
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Le document en format XML
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Tsuchiya</name><name sortKey="Yashima, A" sort="Yashima, A" uniqKey="Yashima A" first="A" last="Yashima">A. Yashima</name></noCountry><country name="Japon"><noRegion><name sortKey="Uchiyama, M" sort="Uchiyama, M" uniqKey="Uchiyama M" first="M" last="Uchiyama">M. Uchiyama</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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